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paper 7, Genomic Comparison of North American Strains of Histoplasma Capsulatum

In Session 1 of Future Computer and Communication 2011 from: International Conference on Future Computer and Communication, 3rd (ICFCC 2011), First
Author(s)/Editor(s):
859711 Cover Image
Published: 2011
Author(s)/Editor(s): Sofia Visa, Stephanie Strand, Tristan Vrolijk
Chapter Page Count: 9 pages

Table of Contents

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Chapter Contents

  • Abstract
  • Key Words
  • 1 Introduction
  • 2. Genome Statistics and Predicted Genes
  • 3. Beanbag Analysis for Orthologs, Paralogs, and Gene Families
  • 4. Experimental Results: Finding Orthologs, Paralogs, and Gene Families
  • 5. Additional Results: Identifying Common Genes
  • 6. Conclusion and Future Work
  • Acknowledgment
  • References

Excerpt

This research shows work in progress in comparing the genomes of two related organisms, namely the two North American strains of Histoplasma Capsulatum, in an effort to understand why one of them (G217B) is more infectious then the other (Wu24). For this we employ bioinformatics analysis tools along with Matlab and Perl programs. The results shown here indicate that the two strains have many genes in common (70%). Also othologs, paralogs, and gene families are reported. Further, corresponding contigs having common genes are found.



©2011 ASME

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Print ISBN:

9780791859711

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