paper 7, Genomic Comparison of North American Strains of Histoplasma Capsulatum
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Chapter Contents
- Abstract
- Key Words
- 1 Introduction
- 2. Genome Statistics and Predicted Genes
- 3. Beanbag Analysis for Orthologs, Paralogs, and Gene Families
- 4. Experimental Results: Finding Orthologs, Paralogs, and Gene Families
- 5. Additional Results: Identifying Common Genes
- 6. Conclusion and Future Work
- Acknowledgment
- References
Excerpt
This research shows work in progress in comparing the genomes of two related organisms, namely the two North American strains of Histoplasma Capsulatum, in an effort to understand why one of them (G217B) is more infectious then the other (Wu24). For this we employ bioinformatics analysis tools along with Matlab and Perl programs. The results shown here indicate that the two strains have many genes in common (70%). Also othologs, paralogs, and gene families are reported. Further, corresponding contigs having common genes are found.
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